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If P(x)=a*x^4+b*x^3+c*x^2+d*x+e x has roots at x=1,2,3 & 4, and P(0)=48, what is p(5)?

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INTEGRATION OF SIN(X) Three groups :: x1,x2,x3
A,b common to all three. Then atleast 1 elemnt common to 2 ie x1,x2,x2,x3,x3,x1.
Findminimum elements in each group.